Students will get acquainted with the structure of cells, their organization into tissues and microscopic structure of organs. Moreover, function of particular cellular structures visible under light and electron microscope and the relationship between function and structure of cells and tissues will be presented. These information constitute basis for cytophysiology, physiology, biochemistry and histopathology. During embryology lectures students will be acquainted with early stages of human embryo and fetus development.
The objectives of Histology and Embryology teaching are achieved when students:
- get familiar with the structure and function of cells, tissues and organs on the level corresponding to the scope of internationally recognized textbooks,
- get acquainted with early stages of human development, structure and function of fetal membranes,
- are able to recognize under the microscope structures of cells and tissues as well as organs of the human body.
The study of Histology with Embryology and Cytophysiology lasts two semesters and ends with an exam at the end of the second semester in the first year of study.
Scope of study material for Cytophisiology (first intermediate examination)
|
Lectures |
ED Lippincott Illustrated Reviews: Cell and Molecular Biology, Third edition |
|
Structure of cell membranes, membrane transport. |
Chapter: 3, 13, 14, 15, 16 |
|
Cytoplasm organization – cytoskeleton and adhesion molecules. Selected cell compartments – mitochondrion. |
Chapter: 2 (fragment), 4, 5 (fragment) |
|
Genome structure, DNA replication, DNA repair, DNA transcription. |
Chapter: 6, 7, 8 (fragment) |
|
Regulation of transcription and translation, cell differentiation. |
Chapter: 1,10 |
|
Protein modifications – post-translational processing, intracellular transport, protein degradation, protein export. |
Chapter: 9, 11, 12 |
|
Cell receptors and signal transduction. |
Chapter: 17, 18, 19 |
|
Cell cycle regulation, cell division. |
Chapter: 20, 21 |
|
Cell aging and death. |
Chapter: 23, 24 |
|
Basics of oncogenesis |
Chapter: 22 |
FORMS OF CLASSES
- lectures: 20 hours
- seminars: 30 hours
- practical classes: 70 hours
Obligatory literature:
- Junqueira's Basic Histology: Text and Atlas, last edition
- Sadler T. W. “Langman’s Medical Embryology”, 2015, Wolters Kluwer Health, thirteenth edition.
- Cell and Molecular Biology Lippincott’s illustrated Review by Chandar, Viselli
Supplementary literature:
Stevens A., Lowe J. “Human Histology” 2005, Elsevier Mosby, third ed.
Ross M.H., Pawlina W. “Histology: A text and atlas”, 2011, Lippincott Williams & Wilkins, sixth ed.
Gartner L. P., “Textbook of Histology”, Elsevier, last edition.
Schoenwolf, Bleyl, Brauer, Francis-West “Larsen's Human Embryology” 5th Ed.
Nanci A. “Ten Cate’s - Oral Histology”, 2008, Elsevier, seventh edition or newer