The aim of the course

Students will get acquainted with the structure of cells, their organization into tissues and microscopic structure of organs. Moreover, function of particular cellular structures visible under light and electron microscope and the relationship between function and structure of cells and tissues will be presented. These information constitute basis for cytophysiology, physiology, biochemistry and histopathology. During embryology lectures students will be acquainted with early stages of human embryo and fetus development.
The objectives of Histology and Embryology teaching are achieved when students:

  • get familiar with the structure and function of cells, tissues and organs on the level corresponding to the scope of internationally recognized textbooks,
  • get acquainted with early stages of human development, structure and function of fetal membranes,
  • are able to recognize under the microscope structures of cells and tissues as well as organs of the human body.

The study of Histology with Embryology and Cytophysiology lasts two semesters and ends with an exam at the end of the second semester in the first year of study.

Scope of study material for Cytophisiology (first intermediate examination)

 

Junqueira's Basic Histology: Text and Atlas, Sixteenth Edition. Anthony Mescher. McGraw Hill / Medical

Lippincott Illustrated Reviews: Cell and Molecular Biology. Nalini Chandar, Susan M. Viselli. Wolters Kluwer Health, edition 1

Seminars and classes

 

 

1. Basic techniques of histological staining, microscopes

Chapter 1

 

2. Cell ultrastructure

 

Chapter 3, 4, 5, 11, 12, 13, 14, 15, 16

3. Cell nucleus, regulation of gene expression

 

Chapter 6, 7, 8, 9, 10

4. Cell signalling

 

Chapter 17, 18 i 19

5. Cell cycle and cel division

 

Chapter 20, 21

6. Differentiation, senescence and cel death

 

Chapter 1, 23, 24

7. Basics of oncogenesis

 

Chapter 22

Lectures

 

 

Cholesterol

 

Chapter 26

Mitochondrion

 

Chapter 5

DNA repair

 

Chapter 7

Regulatory RNA

 

Chapter 10

Proteasomes

 

Chapter 12

Autophagy

 

Chapter 12

 

FORMS OF CLASSES

  • lectures: 20 hours
  • seminars: 30 hours
  • practical classes: 70 hours

Obligatory literature:

  1. Junqueira's Basic Histology: Text and Atlas, last edition
  2. Sadler T. W. “Langman’s Medical Embryology”, 2015, Wolters Kluwer Health, thirteenth edition.
  3. Cell and Molecular Biology Lippincott’s illustrated Review by Chandar, Viselli

Supplementary literature:

Stevens A., Lowe J. “Human Histology” 2005, Elsevier Mosby, third ed.
Ross M.H., Pawlina W.  “Histology: A text and atlas”, 2011, Lippincott Williams & Wilkins, sixth ed.

Gartner L. P., “Textbook of Histology”, Elsevier, last edition.

Schoenwolf, Bleyl, Brauer, Francis-West “Larsen's Human Embryology” 5th Ed.
Nanci A. “Ten Cate’s - Oral Histology”, 2008, Elsevier, seventh edition or newer